Experiment 678653
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRAGASTRIC |
| Organism | Hypericum perforatum (CLUSIACEAE) |
| Citation | NATHAN,PJ:. (1999). THE EXPERIMENTAL AND CLINICAL PHARMACOLOGY OF ST JOHN'S WORT (HYPERICUM PERFORATUM L.).. 4(4) |
| Amount utilized | |
| Compound isolated | |
| Disease | PRE-CLINICAL ANIMALS STUDIES SUGGEST THAT HYPERICUM IS EFFECTIVE IN THREE MAJOR BIOCHEMICAL SYSTEMS RELEVANT FOR ANTIDEPRESSANT ACTIVITY, NAMELY THE INHIBITOR OF THE SYNAPTIC RE-UPTAKE SYSTEM FOR SEOTONIN (5-HT), MORADRENALINE (NA) AND DOPAMINE (DA). |
| Dose amount | VAR |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Dose expression | DOSE |
| Extract | HYDRO-ALCOHOLIC EXT |
| Gender | GIVEN TO BOTH SEXES |