Experiment 68075
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Trifolium pratense (FABACEAE) |
| Citation | FUGH BERMAN,A: KRONENBERG,F:. (2001). RED CLOVER (TRIFOLIUM PRATENSE) FOR MENOPAUSAL WOMEN: CURRENT STATE OF KNOWLEDGE.. 8(5) |
| Amount utilized | |
| Compound isolated | |
| Disease | A REVIEW OF THE CLINICAL TRIALS. TWO DOUBLE-BLIND PLACEBO-CONTROLLED TRIALS FOUND NO BENEFICIAL EFFECTS OF RED CLOVER EXTRACTS ON HOT FLASHES OR OTHER MENOPAUSAL SYMPTOMS. THREE OF FOUR TRIALS EXAMINING THE EFFECT OF RED CLOVER ON LIPIDS FOUND NO BENEFIT; THE FOURTH TRIAL CONTAINS TOO LITTLE DATA TO INTERPRET. ONE STUDY EXAMINING THE EFFECT OF RED CLOVER ON ARTERIAL COMPLIANCE FOUND A SIGNIFICANT BENEFICIAL EFFECT ON ARTERIAL COMPLIANCE. RED CLOVER EXTRACTS HAVE AS YET NO CLEAR DEMONSTRABLE BENEFIT FOR MENOPAUSAL SYMPTOMS. POTENTIAL ESTROGENIC EFFECTS ON BREAST AND ENDOMETRIUM HAVE NOT BEEN ADEQUATELY ASSESSED. THE PRESENCE OF COUMARINS IN SOME CLOVER SPECIES MAKES IT IMPERATIVE TO INCLUDE TESTS OF CLOTTING FACTORS IN FUTURE TRIALS. |
| Dose amount | 40.0 MG |
| Number | 3 |
| Qualitative result | INACTIVE |
| Animal | HUMAN ADULT |
| Per unit | DAY |
| Dose expression | DOSE |
| Extract | ISOFLAVONE FRACTION |
| Gender | FEMALE |