Experiment 68514
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Piper methysticum (PIPERACEAE) |
| Citation | CONNOR,KM: DAVIDSON,JRT: CHURCHILL,LE:. (2001). ADVERSE-EFFECT PROFILE OF KAVA.. 6(10) |
| Amount utilized | |
| Compound isolated | |
| Disease | IN THIS REPORT, THE SAFETY PROFILE FOR KAVA IS PROVIDED, INCLUDING FINDINGS FROM A STUDY OF ITS USE IN GENERALIZED ANXIETY DISORDER. SAFETY PARAMETERS ASSESSED INCLUDE OCCURRENCE OF ADVERSE EVENTS, WITHDRAWAL SYMPTOMS, EFFECT ON HEART RATE, BLOOD PRESSURE, LABORATORY ASSESSMENTS, AND SEXUAL FUNCTION. NO DIFFERENCES WERE FOUND BETWEEN KAVA AND PLACEBO ON ANY OF THE PARAMETERS EVALUATED. THE DATA SUPPORT THE SAFETY OF KAVA IN TREATING ANXIETY AT 280 MG KAVA LACTONES/DAY FOR 4 WEEKS. |
| Dose amount | 280.0 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | DAY |
| Dose expression | DOSE |
| Extract | ETOH(100%)EXT |
| Gender | GIVEN TO BOTH SEXES |