Experiment 68873
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Glycine max (FABACEAE) |
| Citation | SETCHELL,KDR: BROWN,NM: ZIMMER NECHEMIAS,L: BRASHEAR,WT: WOLFE,BE: KIRSCHNER,AS: HEUBI,JE:. (2002). EVIDENCE FOR LACK OF ABSORPTION OF SOY ISOFLAVONE GLYCOSIDES IN HUMANS, SUPPORTING THE CRUCIAL ROLE OF INTESTINAL METABOLISM FOR BIOAVAILABILITY.. 76(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | IN 12 HEALTHY PREMENOPAUSAL WOMEN AGED > 18 YR. ISOFLAVONE GLYCOSIDES ARE NOT ABSORBED INTACT ACROSS THE ENTEROCYTE OF HEALTHY ADULTS, AND THEIR BIOAVAILABILITY REQUIRES INITIAL HYDROLYSIS OF THE SUGAR MOIETY BY INTESTINAL BETA-GLUCOSIDASES FOR UPTAKE TO THE PERIPHERAL CIRCULATION. |
| Dose amount | 50.0 ML |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | ANIMAL |
| Dose expression | CD90 |
| Extract | MILK |
| Gender | FEMALE |