Experiment 69604
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Cimicifuga racemosa (RANUNCULACEAE) |
| Citation | WARNECKE,G:. (1985). INFLUENCE OF A PHYTOPHARMACEUTICAL ON CLIMACTERIC COMPLAINTS.. 36() |
| Amount utilized | |
| Compound isolated | |
| Disease | ATROPHIC CHANGES IN THE VAGINAL MUCOSA. TREATED WITH EITHER THE EXTRACT (40 DROPS TWICE DAILY), CONJUGATED ESTROGENS (0.625 MG DAILY) OR DIAZEPAM (2 MG DAILY) FOR 12 WKS.ALL THREE FORMS OF THERAPY REDUCED ALL THREE INDICATORS. THE EXTRACT AND CONJUGATED ESTROGENS ALSO REDUCED ASSESSMENT OF THE PATIENTS WAS BASED ON 3 INDICATORS: THE MENOPAUSE INDEX (FOR HOT FLASHES, NOCTURNAL SWEATING, NERVOUSNESS,HEADACHE AND PALPITATIONS), AND THE HAMILTON ANXIETY RATING SCALE AND SELFASSESSMENT DEPRESSION SCALE.PATIENTS WERE A RANDOMIZED CONTROLLED TRIAL INVOLVING 60 WOMEN AGED 45-60 YEARS COMPARED THE EFFICACY OF ETHANOL EXTRACT WITH HORMONE REPLACEMENT THERAPY (.6 MG CONJUGATED ESTROGENS) OR 2 MG DIAZEPAM FOR THE TREATMENT OF CLIMACTERIC SYMPTOMS. CLINICAL |
| Dose amount | 2.2 ML |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | DAY |
| Dose expression | DOSE |
| Extract | ETOH(60%)EXT |
| Gender | FEMALE |