| Disease | SCORE AND ATTENTION SPAN COMPARED WITH THE CASE OF PARTICIPANTS RECEIVING NO TREATMENT. HRT AND PL HAD DIFFERENT EFFECTS ON COGNITIVE FUNCTION; HRT IMPROVED DELAYED RECALL, WHEREAS FLEXIBLE THINKING SEEMED IMPROVED IN THE PL GROUP.
SIGNIFICANT CHANGES IN THE LIPID PROFILE OR FOLLICLE-STIMULATING HORMONE AND LUTEINIZING HORMONE WERE OBSERVED IN THE PL GROUP COMPARED WITH THE CONTROLS. HOWEVER, BOTH THE HRT AND PL GROUPS SHOWED AN IMPROVEMENT IN MINI-MENTAL STATE EXAMINATION
FOLLICLE-STIMULATING HORMONE; AND LUTEINIZING HORMONE. ONLY PARTICIPANTS IN THE HRT GROUP SHOWED A MEAN REDUCTION IN CHOLESTESROL AND LOW-DENSITY LIPOPROTEIN CHOLESTEROL THAT WAS SIGNIFICANTLY DIFFERENT FROM THAT OF THE CONTROL GROUP. NO
QUESTIONNAIRE; NEUROPSYCHOLOGICAL TESTS COVERING MEMORY, ATTENTION, MOTOR SPEED, AND WORD-FINDING ABILITY; QUALITY OF LIFE (SF36); LIPID PROFILE; URINARY DEOXYPYRIDINOLINE; DIETARY PHYTOESTROGEN INTAKE AND URINARY PHYTOESTROGEN; ESTRADIOL;
TO 65 YRS WERE RAMDOMIZED TO RECEIVE HRT(N=43), PL (EQUIVALENT TO 100 MG ISOFLAVONE; N=45), OR NO TREATMENT(N=39) FOR 3 MONTHS. THE FOLLOWING MEASUREMENTS WERE CARRIED OUT AT BASELINE AND AFTER 3 MONTHS FOR ALL PARTICIPANTS; MENOPAUSAL SYMPTOMS
TO EXAMINE THE EFFECTS OF PL IN COMPARISON WITH HORMONE REPLACEMENT THERAPY(HRT) ON LIPID PROFILE, SEX HORMONE LEVELS, BONE TURNOVER MARKERS, AND INDICES OF COGNITIVE FUNCTION. IN THE STUDY 127 COMMUNITY-LIVING, POSTMENOPAUSAL WOMEN AGED 50 |