Experiment 704979

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

LAPACHONE,BETA:

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationPINK,JJ: PLANCHON,SM: TAGLIARINO,C: VARNEST,ME: SIEGEL,D: BOOTHMAN,DA:. (2000). NAD(P)H:QUINONE OXIDOREDUCTASE ACTIVITY IS THE PRINCIPAL DETERMINANT OF BETA-LAPACHONE CYTOTOXICITY.. 275(8)
Amount utilized
Compound isolated
DiseaseNQO1 REDUCED BETA-LAPACHONE CYTOTOXICITY IN T47D: A18 CELLS.
Dose amount8.0 MICROMOLS
Number1
Qualitative resultWEAK ACTIVITY
AnimalCELL CULTURE
Dose expressionCONC USED