Experiment 70670

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOEFFECTS DUE TO A COMBINATION OF DRUGSANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

THALICARPINE

Alerts

A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeROUTE NOT GIVEN
OrganismEmpty organism
CitationMILUSHEV,A: DAMYANOVA,M:. (1983). COMBINATION THERAPY OF LYMPHOID LEUKEMIA L-1210 INVOLVING THALIBLASTINE.. 11()
Amount utilized
Compound isolated
DiseaseA THALICARPINE RESISTANT STRAIN WAS USED. ANTITUMOR ACTIVITY WAS,RESTORED WHEN CYCLOPHOSPHAMIDE WAS GIVEN AFTER THALICARPINE. COMBINATION THERAPY WITH BCNU, CCNU, 5-FLUOROURACIL, OR METHOTREXATE WAS INEFFECTIVE.
Number1
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionDOSE