Experiment 714692

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

GERMACRAN-8-ALPHA-12-OLIDE,2-BETA-5-EPOXY-5-10-DIHYDROXY-6-ALPHA-ANGELOYL-OXY-9-BETA-ISO-BUTYL-OXY:

Details

PropertyValue
Pharmacology
NITRIC OXIDE SYNTHESIS INHIBITION
OrganismCarpesium divaricatum (ASTERACEAE)
CitationKIM,EJ: JIN,HK: KIM,YK: LEE,HY: LEE,SY: LEE,KR: ZEE,OP: HAN,JW: LEE,HW:. (2001). SUPPRESSION BY A SESQUITERPENE LACTONE FROM CARPESIUM DIVARICATUM OF INDUCIBLE NITRIC OXIDE SYNTHASE BY INHIBITING NUCLEAR FACTOR-KAPPA B ACTIVATION.. 61(7)
Amount utilized
Compound isolated
DiseaseVS.LPS-STIMULATED NITRITE PRODUCTION.
Dose amount2.16 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50