Experiment 72756

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOEFFECTS DUE TO A COMBINATION OF DRUGSANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

CADEGUOMYCIN

Alerts

RESULTS SIGNIFICANT AT P < 0.01 LEVEL.DOSING ON DAYS 1-10.A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.

Details

PropertyValue
Pharmacology
METASTASIS INHIBITION
Administration routeIP
OrganismStreptomyces hygroscopicus (STREPTOMYCETACEAE)
CitationYUAN,BD: WU,RT: SATO,I: OKABE,T: SUZUKI,H: NISHIMURA,T: TANAKA,N:. (1985). BIOLOGICAL ACTIVITY OF CADEGUOMYCIN. INHIBITION OF TUMOR GROWTH AND METASTASIS, IMMUNOSTIMULATION, AND POTENTIATION OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE.. 38(5)
Amount utilized
Compound isolated
DiseaseSYNERGISTIC ACTIVITY WITH ARA-C AGAINST REGIONAL LYPH NODE METASTASIS
Dose amount4.0 MG
Number11
Percent yield81%
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE
Expression resultILS