Experiment 739755

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

YOHIMBINE

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
MISCELLANEOUS EFFECTS
Administration routeROUTE NOT GIVEN
OrganismEmpty organism
CitationMILLAN,MJ: NEWMAN-TANCREDI,A: AUDINOT,V: CUSSAC,D: LEJEUNE,F: NICOLAS,JP: COGE,F: GALIZZI,JP: BOUTIN,JA: RIVET,JM: KEKEYNE,A: GOBERT,A:. (2000). AGONIST AND ANTAGONIST ACTIONS OF YOHIMBINE AS COMPARED TO FLUPAROXAN AT ALPHA-2-ADRENERGIC RECEPTORS (AR)S, SEROTONIN (5-HT) 1A, 5-HT1B, 5-HT1P AND DOPAMINE D2 AND D3 RECEPTORS. SIGNIFICANCE FOR THE MODULATION OF FRONTOCORTICAL MONOAMINGERIC. 35(2)
Amount utilized
Compound isolated
DiseaseINCREASE DOPAMINE AND NORADRENALINE LEVELS BOTH ALONE AND IN ASSOCIATION WITH FLUPAROXAN.
Number2
Qualitative resultACTIVE
AnimalRAT
Dose expressionDOSE