Experiment 742683

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

SILYMARIN

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.

Details

PropertyValue
Pharmacology
TISSUE INHIBITOR OF METALLOPROTEINASES-1(TIMP-1) INHIBITION
Administration routeINTRAGASTRIC
OrganismEmpty organism
CitationJIA,JD: BAUER,M: CHO,JJ: RUEHIL,M: MILANI,S: BOIGK,G: RIECKEN,EO: SCHUPPAN,D:. (2001). ANTIFIBROTIC EFFECT OF SILYMARIN IN RAT SECONDARY BILIARY FIBROSIS IS MEDIATED BY DOWNREGULATION OF PROCOLLAGEN ALPHA1(I) AND TIMP-1.. 35(3)
Amount utilized
Compound isolated
Dose amount50.0 MG
Number2
Qualitative resultACTIVE
AnimalRAT
Per unitKG
Dose expressionDOSE
GenderFEMALE