Experiment 755714

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CEPHAELINE

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.

Details

PropertyValue
Pharmacology
CYTOCHROME P450 INHIBITION
OrganismEmpty organism
CitationASANO,T: KUSHIDA,H: SADAKANE,C: ISHIHARA,K: WAKUI,Y: YANAGISAWA,T: KIMURA,M: KAMEI,H: YOSHIDA,T:. (2001). METABOLISM OF IPECAC ALKALOIDS CEPHAELINE AND EMETINE BY HUMAN HEPATIC MICROSOMAL CYTOCHROME P450S, AND THEIR INHIBITORY EFFECTS ON P450 ENZYME ACTIVITIES.. 24(6)
Amount utilized
Compound isolated
DiseaseVS.CYP2D6 SUBSTRATE.
Dose amount121.0 MICROMOLS
Number1
Qualitative resultACTIVE
AnimalHUMAN ADULT
Dose expressionIC50