Experiment 757070

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

AESCULETIN

Alerts

DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
COLLAGENOLYTIC INHIBITION
Administration routeINTRAGASTRIC
OrganismEmpty organism
CitationYAMADA,H: WATANABE,K: SAITO,T: HAYASHI,H: NIITANI,Y: KIKUCHI,T: ITO,A: FUJIKAWA,K: LOHMANDER,LS:. (1999). ESCULETIN (DIHYDROXYCOUMARIN) INHIBITS THE PRODUCTION OF MATRIX METALLOPROTEINASES IN CARTILAGE EXPLANTS, AND ORAL ADMINISTRATION OF ITS PRODRUG, CPA-926, SUPPRESSES CARTILAGE DESTRUCTION IN RABBIT EXPERIMENTAL OSTEOARTHRITIS.. 26(3)
Amount utilized
Compound isolated
Dose amount200.0 MG
Number2
Qualitative resultACTIVE
AnimalRABBIT
Per unitKG
Dose expressionDOSE