Experiment 760857

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

COSTUNOLIDE

Details

PropertyValue
Pharmacology
NITRIC OXIDE RELEASE INHIBITION
OrganismLaurus nobilis (LAURACEAE)
CitationMATSUDA,H: KAGERURA,T: TOGUCHIDA,I: UEDA,H: MORIKAWA,T: YOSHIKAWA,M:. (2000). INHIBITORY EFFECTS OF SESQUITERPENENES FROM BAY LEAF ON NITRIC OXIDE PRODUCTION IN LIPOPOLYSACCHARIDE-ACTIVATED MACROPHAGES: STRUCTURE REQUIREMENT AND ROLE OF HEART SHOCK PROTEIN INDUCTION.. 66(22)
Amount utilized
Compound isolated
DiseaseVS.LPS-STIMULATED CELLS.
Dose amount1.2 MICROMOLS
Number5
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50