Experiment 764428

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PIPERINE

Details

PropertyValue
Pharmacology
P-GLYCOPROTEIN REVERSAL ACTIVITY
OrganismEmpty organism
CitationBHARDWAJ,RK: GLAESER,H: BECQUEMONT,L: KLOTZ,U: GUPTA,SK: FROMM,MF:. (2002). PIPERINE, A MAJOR CONSTITUENT OF BLACK PEPPER, INHIBITS HUMAN P-GLYCOPROTEIN AND CYP3A4.. 302(2)
Amount utilized
Compound isolated
DiseaseINHIBITED CYCLOSPORINE A TRANSPORT.
Dose amount74.1 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50