Experiment 771386

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

HYMENIALDISINE,CIS-10: DEBROMO:

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismStylissa massa (AXINELLIDAE)
CitationTASDEMIR,D: MALLON,R: GREENSTEIN,M: FELDBERG,LR: KIM,SC: COLLINS,K: WOJCIECHOWICZ,D: MANGALINDAN,GC: CONCEPCION,GP: HARPER,MK: TRELAND,CM:. (2002). ALDISINE ALKALOIDS FROM THE PHILIPPINE SPONGE STYLISSA MASSA ARE POTENT INHIBITORS OF MITOGEN-ACTIVATED PROTEIN KINASE KINASE-1 (MEK-1).. 45()
Amount utilized
Compound isolated
Dose amount>10.0 MICROMOLS
Number12
Qualitative resultINACTIVE
AnimalCELL CULTURE
Dose expressionIC50