Experiment 776067

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

COMBRETASTATIN A-4

Details

PropertyValue
Pharmacology
ANTITUBULIN ACTIVITY
OrganismEmpty organism
CitationWANG,L: WOODS,KW: LI,Q: BARR,KJ: MC CROSKEY,RW: HANNICK,SM: GHERKE,L: CREDO,RB: HUI,YH: MARSH,K: WARNER,R: LEE,JY: ZIELNSKI-MOZNG,N: FROST,D: ROSENBERG,SH: SHAM,HL:. (2002). POTENT, ORALLY ACTIVE HETEROCYCLE-BASED COMBRETASTATIN A-4 ANALOGUES: SYNTHESIS, STRUCTURE-ACTIVITY RELATIONSHIP, PHARMACOKINETICS, AND IN VIVO ANTITUMOR ACTIVITY EVALUATION.. 45(8)
Amount utilized
Compound isolated
Dose amount1.2 MICROMOLS
Number3
Qualitative resultACTIVE
Dose expressionIC50