Experiment 77719

Worktypes

EFFECTS DUE TO A COMBINATION OF DRUGSANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

VINDESINE*

Alerts

A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationKANZAWA,F: MATSUSHIMA,Y: ISHIHARA,J-I: SHIMIZU,E: SASAKI,Y: SAIJO,N: MIYAZAWA,N:. (1985). THE USE OF HUMAN TUMOR CLONOGENIC ASSAY IN PREDICTING COMBINATION EFFECT OF CISPLATIN PLUS VINDESINE IN CARCINOMA OF THE LUNG.. 8(10)
Amount utilized
Compound isolated
DiseaseTHERE WAS A SYNERGISTIC EFFECT IN 10 OF 17 EXPLANTS, WHEN TREATED WITH CISPLATINE (0.2 UG/ML).
Dose amount5.0 NG
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Per unitML
Dose expressionCONC USED