Experiment 781795

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SOPHORANONE

Details

PropertyValue
Pharmacology
MITOGEN-ACTIVATED PROTEIN KINASE INHIBITION
OrganismEmpty organism
CitationKAJIMOTO,S: TAKANASHI,N: KAJIMOTO,T: XU,M: CAO,JD: MASUDA,Y: AIUCHI,T:. (2002). SOPHORANONE, EXTRACTED FROM A TRADITIONAL CHINESE MEDICINE SHAN DOU GEN, INDUCES APOPTOSIS IN HUMAN LEUKEMIA U937 CELLS VIA FORMATION OF REACTIVE OXYGEN SPECIES AND OPENING OF MITOCHONDRIAL PERMEABILITY TRANSITION PORES.. 99(6)
Amount utilized
Compound isolated
Dose amount30.0 MICROMOLS
Number14
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED