Experiment 809777

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODESTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

VINCALEUKOBLASTINE

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismEmpty organism
CitationBARNETT,CJ: CULLINAN,GJ: GERZON,K: HOYING,RC: JONES,WE: NEWLON,WM: POORE,GA: ROBISON,RL: SWEENEY,MJ: TODD,GC: DYKE,RW: NELSON,RL:. (1978). STRUCTURE-ACTIVITY RELATIONSHIPS OF DIMERIC CATHARANTHUS ALKALOIDS. 1. DEACETYLVINBLASTINE AMIDE (VINDESINE SULFATE).. 21()
Amount utilized
Compound isolated
DiseaseDOSED ON DAY 1 ONLY
Dose amount2.7 MG
Number10
Percent yield81%
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE
Expression resultILS