Experiment 809915

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODESTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

MAYTANSINOL-3-CROTONATE

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationKUPCHAN,SM: SNEDEN,AT: BRANFMAN,AF: HOWIE,GA: REBHUN,LI: MC IVOR,WE: WANG,RW: SCHNAITMAN,TC:. (1978). TUMOR INHIBITORS. 124. STRUCTURAL REQUIREMENTS FOR ANTILEUKEMIC ACTIVITY AMONG THE NATURALLY OCCURRING AND SEMISYNTHETIC MAYTANSINOIDS.. 21()
Amount utilized
Compound isolated
Dose amount0.36 NANOMOLS
Number1
Qualitative resultSTRONG ACTIVITY
AnimalCELL CULTURE
Per unitLITER
Dose expressionED50