Experiment 813433
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV |
| Organism | Maytenus buchananii (CELASTRACEAE) |
| Citation | CABANILLAS,F: RODRIGUEZ,V: HALL,SW: BURGESS,MA: BODEY,GP: FREIREICH,EJ:. (1978). PHASE 1 STUDY OF MAYTANSINE USING A 3-DAY SCHEDULE.. 62() |
| Amount utilized | |
| Compound isolated | |
| Disease | THIS WAS A PHASE I STUDY 42/60 PATIENTS WITH METASTATIC MALIGNANCY WERE TREATED AND EVALUABLE ACTIVITY WAS DOSE RELATED |
| Dose amount | 0.30 MG |
| Number | 5 |
| Qualitative result | INACTIVE |
| Animal | HUMAN ADULT |
| Per unit | SQ M BODY SURFACE |
| Dose expression | DOSE |
| Gender | GIVEN TO BOTH SEXES |