Experiment 813477
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV INFUSION |
| Organism | Maytenus buchananii (CELASTRACEAE) |
| Citation | CHABNER,BA: LEVINE,AS: JOHNSON,BL: YOUNG,RC:. (1978). INITIAL CLINICAL TRIALS OF MAYTANSINE, AN ANTITUMOR PLANT ALKALOID.. 62() |
| Amount utilized | |
| Compound isolated | |
| Disease | PHASE I CLINICAL TRIAL IN CANCER PATIENTS-PATIENTS DOSED ONCE EACH WEEK RESPONSE IN TWO PATIENTS WITH ACUTE LYMPHOCYTIC LEUKEMIA |
| Dose amount | <2.0 MG |
| Number | 4 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | SQ M BODY SURFACE |
| Dose expression | DOSE |