Experiment 837192

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PUMILIOTOXIN A

Details

PropertyValue
Pharmacology
TACHYCARDIA ACTIVITY
OrganismEmpty organism
CitationDALY,JW: MC NEAL,ET: OVERMAN,LE: ELLISON,DH:. (1985). A NEW CLASS OF CARDIOTONIC AGENTS: STRUCTURE-ACTIVITY CORRELATIONS FOR NATURAL AND SYNTHETIC ANALOGUES OF THE ALKALOID PUMILIOTOXIN B (8-HYDROXY-8-METHYL-6-ALKYLIDENE-1-AZABICYCLO(4.3.0)NONANES).. 28(4)
Amount utilized
Compound isolated
DiseaseFORCE OF CONTRACTION WAS INCREASED.
Dose amount30.0 MICROMOLS
Number2
Qualitative resultWEAK ACTIVITY
AnimalGUINEA PIG
Dose expressionCONC USED