Experiment 851853

Worktypes

REVIEW OFEFFECTS DUE TO A COMBINATION OF DRUGSANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN HUMANS

Compounds isolated

LEUROCRISTINE

Alerts

THESE DATA ARE FROM A REVIEW ARTICLE.

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIV
OrganismEmpty organism
CitationCHANG,CN:. (1984). ANTI-LEUKEMIA CHINESE HERBS AND THE EFFECTIVE INGREDIENTS.. ()
Amount utilized
Compound isolated
DiseaseCOMBINED THERAPY OF LEUROCRISTINE WITH HARRINGTONINE, ARA-C AND PREDNISONE PRODUCED A COMPLETE REMISSION RATE OF 60-80% IN PATIENTS WITH ACUTE NON-LYMPHOCYTIC LEUKEMIA. ACUTE NON-MONOCYTIC, PROMYELOCYTIC AND ERYTHROCYTIC LEUKEMIA WERE ALSO TREATED EFFECTIVELY.
Number1
Qualitative resultACTIVE
AnimalHUMAN ADULT
Dose expressionDOSE