Experiment 855728

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

QUINOLIN-2-4-DIONE,1-2-3-4-TETRAHYDRO: 3-N-HEPTYL-3-HYDROXY:

Details

PropertyValue
Pharmacology
LIPOXYGENASE,5: INHIBITION
OrganismPseudomonas methanica (PSEUDOMONADACEAE)
CitationKITAMURA,S: HASHIZUME,K: IIDA,T: MIYASHITA,E: SHIRAHATA,K: KASE,H:. (1986). STUDIES ON LIPOXYGENASE INHIBITORS. II. KF8940 (2-N-HELPTYL-4-HYDROXYQUINOLINE-N-OXIDE), A POTENT AND SELECTIVE INHIBITOR OF 5-LIPOXYGENASE, PRODUCED BY PSEUDOMONAS METHANICA.. 39(8)
Amount utilized
Compound isolated
Dose amount80.0 MICROMOLS
Number6
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50