Experiment 855734

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

QUINOLINE,2-N-HEPTYL-4-HYDROXY:

Details

PropertyValue
Pharmacology
CYCLOOXYGENASE INHIBITION
OrganismPseudomonas methanica (PSEUDOMONADACEAE)
CitationKITAMURA,S: HASHIZUME,K: IIDA,T: MIYASHITA,E: SHIRAHATA,K: KASE,H:. (1986). STUDIES ON LIPOXYGENASE INHIBITORS. II. KF8940 (2-N-HELPTYL-4-HYDROXYQUINOLINE-N-OXIDE), A POTENT AND SELECTIVE INHIBITOR OF 5-LIPOXYGENASE, PRODUCED BY PSEUDOMONAS METHANICA.. 39(8)
Amount utilized
Compound isolated
Dose amount0.28 MILLIMOLS
Number12
Qualitative resultACTIVE
AnimalCOW
Dose expressionIC50