Experiment 873515
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | SUN,D: COURTNEFY,HS: BEACHEY,EH:. (1988). BERBERINE SULFATE BLOCKS ADHERENCE OF STREPTOCOCCUS PYOGENES TO EPITHELIAL CELLS, FIBRONECTIN, AND HEXADECANE.. 32(9) |
| Amount utilized | |
| Compound isolated | |
| Disease | BACTERIOSTATIC ACTIVITY IS DUE TO THE INHIBITION OF STREPTOCOCCAL ATTACHMENT TO HOST CELLS, WHICH OCCURS AT A CONCENTRATION OF 5 MCG/ML. BERBERINE SULFATE PREVENTS THE FORMATION OF COMPLEXES BETWEEN HOST CELL FIBRONECTIN AND STREPTOCOCCAL LTA. |
| Dose amount | 30.0 MCG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | BROTH CULTURE |
| Per unit | ML |
| Dose expression | TOXIC DOSE |