Experiment 878393

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

MEVINOLIN

Details

PropertyValue
Pharmacology
HYDROXYMETHYLGLUTARYL-CO-A REDUCTASE INDUCTION
Administration routeIN RATION
OrganismEmpty organism
CitationSINGER,II: SCOTT,S: KAZAZIS,DM: HUFF,JW:. (1988). LOVASTATIN, A INHIBITOR OF CHOLESTEROL SYNTHESIS, INDUCES HYDROXYMETHYLGLUTARYL-COENZYME A REDUCTASE DIRECTLY ON MEMBRANES OF EXPANDED SMOOTH ENDOPLASMIC RETICULUM IN RAT HEPATOCYTES.. 85(14)
Amount utilized
Compound isolated
Dose amount0.25 % OF DIET
Number1
Qualitative resultACTIVE
AnimalRAT
Dose expressionDOSE