Experiment 880625
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IP |
| Organism | Glycyrrhiza glabra (FABACEAE) |
| Citation | KAWAKITA,T: YAMADA,A: MITSUYAMA,M: KUMAZAWA,Y: NOMOTO,K:. (1988). PROTECTIVE EFFECT OF A TRADITIONAL CHINESE MEDICINE, XIAO-CHAI-HU-TANG (JAPANESE NAME: SHOSAIKO-TO), ON LISTERIA MONOCYTOGENES INFECTION IN MICE.. 10(3) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE PRESCRIPTION INCLUDED BUPLEURUM CHINENSE(RT), PINELLIA TERNATA(TU), SCUTELLARIA BAICALENSIS(RT), ZIZYPHUS JUJUBA(FR), PANAX GINSENG(RT), GLYCYRRHIZA GLABRA(RT) AND ZINGIBER OFFICINALE(RZ). THE EXTRACT CONTAINED BAICALIN, GLYCYRRHIZIN AND TOTAL SAIKOSAPONINS AS KNOWN COMPONENTS. LETHAL EFFECTS OF LISTERIA INFECTION WERE PREVENTED. DOSING 4 DAYS PRIOR TO INFECTION. INCREASED NUMBERS OF MACROPHAGES WERE OBSERVED IN THE PERITONEAL CAVITY, AND THEIR BACTERICIDAL ACTIVITY WAS MAINTAINED AFTER BACTERIAL INFECTION. |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | MOUSE |
| Dose expression | DOSE |
| Extract | HOT H2O EXT |