Experiment 891359

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODESTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PODOPHYLLOTOXIN,4'-DEMETHYL:

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationLEE,KH: IMAKURA,Y: HARUNA,M: BEERS,SA: THURSTON,LS: DAI,HJ: CHEN,CH: LIU,SY: CHENG,YC:. (1989). ANTITUMOR AGENTS. 107. NEW CYTOTOXIC 4-ALKYLAMINO ANALOGUES OF 4'-DEMETHYL-EPIPODOPHYLLOTOXIN AS INHIBITORS OF HUMAN DNA TOPOISOMERASE II.. 52(3)
Amount utilized
Compound isolated
Dose amount0.045 MCG
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Per unitML
Dose expressionED50