Experiment 903535

Worktypes

ANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

GOSSYPOL,(+):

Alerts

TOXIC EFFECTS REPORTED AT ACTIVE DOSE LEVELS.

Details

PropertyValue
Pharmacology
ANTIVIRAL ACTIVITY
OrganismEmpty organism
CitationLIN,TS: SCHINAZI,R: GRIFFITH,BP: AUGUST,EM: ERIKSSON,BFH: ZHENG,DK: HUANG,L: PRUSOFF,WH:. (1989). SELECTIVE INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REPLICATION BY THE (-) BUT NOT THE (+) ENANTIOMER OF GOSSYPOL.. 33(12)
Amount utilized
Compound isolated
DiseaseVIRUS GROWN IN PBM CELLS.
Dose amount50.7 MICROMOLS
Number2
Qualitative resultWEAK ACTIVITY
AnimalCELL CULTURE
Dose expressionIC50