Experiment 917672
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV |
| Organism | Empty organism |
| Citation | FUJII,T: MIYAZAKI,H: NAMBU,K: KAGEMOTO,A: HASHIMOTO,M:. (1984). DISPOSITION AND METABOLISM OF 14C-DEHYDROCORYDALINE IN MICE AND RATS.. 33(8) |
| Amount utilized | |
| Compound isolated | |
| Disease | MAXIMUM BLOOD LEVEL WAS 0.5 MCG/ML. RADIOACTIVITY WAS DISTRIBUTED IN THE GI TRACT, LIVER AND KIDNEYS. MOST ACTIVITY WAS EXCRETED IN THE FECES. EXCRETION VIA URINE AND BILE WAS MINOR. METABOLITE ANALYSIS SUGGESTED THAT THE COMPOUND WAS METABOLIZED VIA O-DEMETHYLATION AND SUBSEQUENT CONJUGATION WITH GLUCURONIC ACID. |
| Dose amount | 6.8 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | MOUSE |
| Per unit | KG |
| Dose expression | DOSE |