Experiment 917695

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOEFFECTS DUE TO A COMBINATION OF DRUGSANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

QUERCETIN

Alerts

A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.

Details

PropertyValue
Pharmacology
ANTIPROLIFERATION ACTIVITY
Administration routeIP
OrganismEmpty organism
CitationHOFMANN,J: FIEBIG,HH: WINTERHALTER,BR: BERGER,DP: GRUNICKE,H:. (1990). ENHANCEMENT OF THE ANTIPROLIFERATIVE ACTIVITY OF CIS-DIAMMINEDICHLOROPLATINUM (II) BY QUERCETIN.. 45(3)
Amount utilized
Compound isolated
DiseaseCONCOMMITANT TREATMENT OF MICE WITH QUERCETIN AND 3 MG CIS-DIAMMINEDICHLOROPLATINUM PER KG REDUCED TUMOR GROWTH TO A SIGNIFICANTLY GREATER DEGREE THAN CIS-DDP ALONE.
Dose amount20.0 MG
Number2
Qualitative resultACTIVE
AnimalMOUSE(NUDE)
Per unitKG
Dose expressionDOSE