Experiment 918030

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CASTANOSPERMINE

Details

PropertyValue
Pharmacology
N-LINKED OLIGOSACCHARIDE NEURONAL PROTEIN INHIBITION
OrganismEmpty organism
CitationRATNER,N: ELBEIN,A: BUNGE,MB: PORTER,S: BUNGE,RP: GLASER,L:. (1986). SPECIFIC ASPARAGINE-LINKED OLIGOSACCHARIDES ARE NOT REQUIRED FOR CERTAIN NEURON-NEURON AND NEURON-SCHWANN CELL INTERACTIONS.. 103()
Amount utilized
Compound isolated
DiseaseCASTANOSPERMINE INHIBITED NEURITE OUTGROWTH, STIMULATED NEURITE FASICULATION, SHOWED NO INFLUENCE ON NEURON-SCHWANN CELL ADHESION, DIMINISHED EXTRACELLULAR MATRIX DEPOSITION AND MYELINATION OF NEURONS AND INHIBITED BASAL LAMINA FORMATION.
Dose amount250.0 MCG
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Per unitML
Dose expressionCONC USED