Experiment 928113

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

MEVINOLIN

Details

PropertyValue
Pharmacology
GLUTARYL CO-A REDUCTASE(BETA-HYDROXY-BETA-METHYL)INHIBITION
OrganismEmpty organism
CitationSINENSKY,M: BECK,LA: LEONARD,S: EVANS,R:. (1990). DIFFERENTIAL INHIBITORY EFFECTS OF LOVASTATIN ON PROTEIN ISOPRENYLATION AND STEROL SYNTHESIS.. 265(32)
Amount utilized
Compound isolated
Disease50% INHIBITION OF CONVERSIONS OF PRO-P21-RAS TO M-P21-RAS AND PRELAMINA TO LAMINA, VIA ISOPRENYLATION.
Dose amount1.0 MCG
Number4
Qualitative resultACTIVE
AnimalCELL CULTURE
Per unitML
Dose expressionIC50