Experiment 928137

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

MANNOSTATIN A

Details

PropertyValue
Pharmacology
ALPHA-MANNOSIDASE INHIBITION
OrganismEmpty organism
CitationTROPEA,JE: KAUSHA,GP: PASTUSZAK,I: MITCHELL,M: AOYAGI,T: MOLYNEUX,RJ: ELBEIN,AD:. (1990). MANNOSTATIN A, A NEW GLYCOPROTEIN-PROCESSING INHIBITOR.. 29(43)
Amount utilized
Compound isolated
DiseaseCOMPETITIVE INHIBITOR OF RAT LIVER LYSOSOMAL ALPHA-MANNOSIDASE. ACETYLATION OF THE AMINO GROUP OF MANNOSTATIN A DESTROYS THIS INHIBITORY EFFECT.
Dose amount160.0 NANOMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50