Experiment 928769

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODESTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

ETOPOSIDE*

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationSINHA,BK: POLITI,PM: ELIOT,HM: KERRIGAN,D: POMMIER,Y:. (1990). STRUCTURE-ACTIVITY RELATIONS, CYTOTOXICITY AND TOPOISOMERASE II DEPENDENT CLEAVAGE INDUCED BY PENDULUM RING ANALOGUES OF ETOPOSIDE.. 26(5)
Amount utilized
Compound isolated
DiseaseTUMOR CELL SURVIVAL WAS EXAMINED 12-14 DAYS AFTER A 1 HOUR INCUBATION AT THE GIVEN DOSE.
Dose amount5.0 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED