Experiment 929058
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IP |
| Organism | Empty organism |
| Citation | KIM,HS: LEE,MK: BAEK,DY: HWANG,SL: CHOI,KJ: KIM,SC:. (1989). EFFECTS OF GINSENOSIDES ON THE DEVELOPMENT OF MORPHINE-INDUCED TOLERANCE AND PHYSICAL DEPENDENCE IN MICE.. 20(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | 40 MG/KG MORPHINE GIVEN EVERY 8 HOURS FOR 6 DAYS. DOSE OF COMPOUND GIVEN DAILY ONE HOUR BEFROE LAST MORPHINE ADMINISTRATION FOR DAY. ANALGESIA WAS 13.3 TIMES THAT OF CONTROL. BODY WEIGHT LOSS WAS 9% VS.19.5% FOR CONTROL. NALOXONE-INDUCED JUMPING RESPONSE INHIBITED BY 50%. |
| Dose amount | 100.0 MG |
| Number | 3 |
| Qualitative result | ACTIVE |
| Animal | MOUSE |
| Per unit | KG |
| Dose expression | DOSE |