Experiment 929127
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | CHAO,NJ: AIHARA,M: BLUME,KG: SIKIC,BI:. (1990). MODULATION OF ETOPOSIDE (VP-16) CYTOTOXICITY BY VERAPAMIL OR CYCLOSPORINE IN MULTIDRUG-RESISTANT HUMAN LEUKEMIC CELL LINES AND NORMAL BONE MARROW.. 18(11) |
| Amount utilized | |
| Compound isolated | |
| Disease | VERAPAMIL OR CYCLOSPORINE DID NOT INCREASE CYTOTOCICITY TOWARD DRUG-SENSITIVE STRAIN. BUT CYCLOSPORINE DID INCREASE CYTOTOXICITY TOWARDS MULTIDRUG-RESISTANT STRAIN CEM/VLB. |
| Dose amount | 2.0 MICROMOLS |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | CELL CULTURE |
| Dose expression | IC50 |