Experiment 930283

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

RICIN A CHAIN

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismEmpty organism
CitationJAFFREZOU,JP: LEVADE,T: KUHLEIN,E: THURNEYSSEN,O: CHIRON,M: GRANDJEAN,H: CARRIERE,D: LAURENT,G:. (1990). ENHANCEMENT OF RICIN A CHAIN IMMUNOTOXIN ACTIVITY BY PERHEXILINE ON ESTABLISHED AND FRESH LEUKEMIC CELLS.. 50(17)
Amount utilized
Compound isolated
DiseaseCYTOTOXICITY OF RICIN A CHAIN, CONJUGATED TO MONOCLONAL ANTIBODY HNC-241, TOWARDS GIVEN CELL LINE IS ENHANCED 10 FOLD BY CO-ADMINISTRATION OF PERHEXILINE.
Dose amount1.0 NANOMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50