Experiment 930748
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IN RATION |
| Organism | Gymnema sylvestre (ASCLEPIADACEAE) |
| Citation | SHANMUGASUNDARAM,ERB: LEELA GOPINATH,K: SHANMUGASUNDARAM,KR: RAJENDRAN,VM:. (1990). POSSIBLE REGENERATION OF THE ISLETS OF LANGERHANS IN STREPTOZOTOCIN-DIABETIC RATS GIVEN GYMNEMA SYLVESTRE LEAF EXTRACTS.. 30(3) |
| Amount utilized | |
| Compound isolated | |
| Disease | AN EXTRACT DESIGNATED AS GS3 WAS USED IN THE STUDY. DOSING WAS FOR 60 DAYS. BLOOD GLUCOSE DROPPED AND INSULIN LEVELS WERE NORMALIZED IN THE STREPTOZOTOCIN-TREATED ANIMALS. IN DIABETIC RAT PANCREAS, THE RATS TREATED WITH THE EXTRACT WERE ABLE TO DOUBLE THE ISLET NUMBER AND BETA CELL NUMBER. |
| Dose amount | 20.0 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | ANIMAL |
| Dose expression | DOSE |
| Extract | ETOH(95%)EXT |
| Gender | MALE |