Experiment 933562
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRAGASTRIC |
| Organism | Empty organism |
| Citation | SMITH,TJ: GUO,Z: THOMAS,PE: CHUNG,FL: MORSE,MA: ELKIND,K: YANG,CS:. (1990). METABOLISM OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE IN MOUSE LUNG MICROSOMES AND ITS INHIBITION BY ISOTHIOCYANATES.. 50(21) |
| Amount utilized | |
| Compound isolated | |
| Disease | MIXED INHIBITION OBSERVED, THE COMPETITIVE COMPONENT HAVING K-I OF 90 NANOMOLAR. ENZYME ACTIVITY ASSAYED 2 HRS AFTER ADMINISTRATION OF DOSE BY LOOKING AT OXIDATIVE METABOLISM OF 4-(METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE. |
| Dose amount | 100.0 MICROMOLS |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | MOUSE |
| Dose expression | CONC USED |
| Gender | FEMALE |