Experiment 933570

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

SARAFOTOXIN A

Details

PropertyValue
Pharmacology
VASODILATOR ACTIVITY
Administration routeIV
OrganismEmpty organism
CitationKITAZUMI,K: SHIBA,T: NISHIKI,K: FURUKAWA,Y: TAKASAKI,C: TASAKA,K:. (1990). VASODILATOR EFFECTS OF SARAFOTOXINS AND ENDOTHELIN-1 IN SPONTAENOUSLY HYPERTENSIVE RATS AND RAT ISOLATED PERFUSED MESENTERY.. 40(8)
Amount utilized
Compound isolated
DiseaseIN SPONTANEOUSLY HYPERTENSIVE RATS, ENDOTHELIUM-DEPENDENT EFFECT WAS INHIBITED BY METHYLENE BLUE. MAXIMUM VASODILATION AT GIVEN DOSE (VS.THAT PRODUCED BY CARBACHOL) WAS 81.7%.
Dose amount1.0 NANOMOLS
Number1
Qualitative resultACTIVE
AnimalRAT
Per unitKG
Dose expressionDOSE