Experiment 938353

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

GLYCYRRHETINIC ACID,18-ALPHA:

Details

PropertyValue
Pharmacology
ORNITHINE DECARBOXYLASE INHIBITION
Administration routeEXTERNAL
OrganismEmpty organism
CitationWANG,ZY: AGARWAL,R: ZHOU,ZC: BICKERS,DR: MUKHTAR,H:. (1991). INHIBITION OF MUTAGENICITY IN SALMONELLA TYPHIMURIUM AND SKIN TUMOR INITIATING AND TUMOR PROMOTING ACTIVITIES IN SENCAR MICE BY GLYCYRRHETINIC ACID: COMPARISON OF 18ALPHA- AND 18BETA-STEREOISOMERS.. 12(2)
Amount utilized
Compound isolated
DiseaseVS.12-O-TETRADECANYLPHORBOL-13-ACETATE-INDUCED ORNIHINE DECARBOXYLASE ACTIVITY. ACTIVITY WAS INHIBITED BY 79%.
Dose amount30.0 MICROMOLS
Number6
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionDOSE