Experiment 938375
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV |
| Organism | Empty organism |
| Citation | WAWRYNCZAK,EJ: CUMBER,AJ: HENRY,RV: PARNELL,GD:. (1991). COMPARATIVE BIOCHEMICAL, CYTOTOXIC AND PHARMACOKINETIC PROPERTIES OF IMMUNOTOXINS MADE WITH NATIVE RICIN A CHAIN, RICIN A1 CHAIN AND RECOMBINANT RICIN A CHAIN.. 47(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | CLEARANCE FROM CIRCULATION WAS BY BIPHASIC KINETICS THAT WERE DESCRIBED BY A 2-COMPARTMENT OPEN PHARMACOKINETIC MODEL. THE ALPHA HALF-LIFE WAS 1.9 HOURS AND THE BETA HALF-LIFE PHASE WAS 11.2 HOURS. |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Dose expression | DOSE |