Experiment 938637
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRADERMAL |
| Organism | Quillaja saponaria (ROSACEAE) |
| Citation | KENSIL,CR: PATEL,U: LENNICK,M: MARCIANI,D:. (1991). SEPARATION AND CHARACTERIZATION OF SAPONINS WITH ADJUVANT ACTIVITY FROM QUILLAJA SAPONARIA MOLINA CORTEX.. 146(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | QS-21, A HYDROPHOBIC SAPONIN COMPONENT WITH NO OR LOW TOXICITY, WAS DEMONSTRATED TO BOOST ANTIBODY (IGG) LEVELS BY 100-FOLD OR MORE WHEN USED IN MOUSE IMMUNIZATIONS WITH THE ANTIGEN BSA AND BEEF LIVER CYTOCHROME B5. |
| Dose amount | 5.0 MCG |
| Number | 6 |
| Qualitative result | ACTIVE |
| Animal | MOUSE |
| Dose expression | DOSE |