Experiment 938891

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

SILYMARIN

Details

PropertyValue
Pharmacology
ANTIHEPATOTOXIC ACTIVITY
Administration routeIP
OrganismEmpty organism
CitationMEREISH,KA: BUNNER,DL: RAGLAND,DR: CREASIA,DA:. (1991). PROTECTION AGAINST MICROCYSTIN-LR-INDUCED HEPATOTOXICITY BY SILYMARIN: BIOCHEMISTRY, HISTOPATHOLOGY, AND LETHALITY.. 8(2)
Amount utilized
Compound isolated
DiseaseVS.MICROCYSTIN LR-INDUCED HEPATOTOXICITY. LETHAL EFFECTS, PATHOLOGICAL CHANGES IN THE LIVER AND DECREASED LEVELS OF SORBITOL DEHYDROGENASE, ALANINE AMINOTRANSFERASE AND LACTATE DEHYDROGENASE WERE INHIBITED.
Dose amount0.5 GM
Number2
Qualitative resultACTIVE
AnimalRAT
Per unitKG
Dose expressionDOSE