Experiment 939389

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

BRYOSTATIN 1

Details

PropertyValue
Pharmacology
TOPOISOMERASE II INHIBITION
OrganismEmpty organism
CitationZWELLING,LA: CHAN,D: ALTSCHULER,E: MAYES,J: HINDS,M: PETTIT,GR:. (1991). EFFECT OF BYOSTATIN 1 ON DRUG-INDUCED, TOPOISOMERASE II-MEDIATED DNA CLEAVAGE AND TOPOISOMERASE II GENE EXPRESSION IN HUMAN LEUKEMIA CELLS.. 41(5)
Amount utilized
Compound isolated
DiseaseVS.PHORBOL-12-MYRISTATE 13-ACETATE- OR ETOPOSIDE-INDUCED TOPOISOMERASE-2 DNA CLEAVAGE.
Dose amount1000 NANOMOLS
Number2
Qualitative resultINACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED